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Compounded medications are not FDA-approved, and their safety and efficacy have not been independently verified by the FDA

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Through the ADR-AMPK axis-mediated phosphorylation of DRP1 at Ser616, PAGln drives mitochondrial fragmentation, membrane potential depolarization, and ROS accumulation, culminating in DNA damage, cell cycle arrest, and dose-dependent senescence in human cells (Yang et al., 2025)

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